Eupatorium perfoliatum


Brunell, M. (2011). Eupatorium perfoliatum; Boneset. Retrieved from:

Botanical Name: Euphatorium perfoliatum

Common name: Boneset (Hoffmann, 2003, p. 549)

Family: Asteraceae (Hoffmann, 2003, p. 549)

Parts used: Dried arieal parts (Hoffmann, 2003, p. 549)


  • Sesquiterpene lactones: eupafolin, euperfolitin, eufoliatorin, euperfolide, eucannabinolide and helenalin.
  • Immunostimulatory polysaccharides
  • Flavonoids: quercetin, kaempferol, hyperoside, astragalin, rutin, eupatorin
  • Sterols
  • Volatile oil

(Hoffmann, 2003, p. 549)



  • Antispasmodic
  • Astringent
  • Bitter
  • Carminative
  • Diaphoretic
  • Immunostimulant
  • Laxative
  • Tonic

(Hoffmann, 2003, p. 549)



Native to North America, used by Native Americans to treat fevers including Dengue fever and malaria (Giese, Brigham, Costa, Le, Ulbricht & Weissner, 2013).



  • Symptoms of influenza (including aches, pains and fever) (Hoffmann, 2003, p. 549)
  • Clears upper respiratory tract of mucus congestion (Hoffmann, 2003, p. 549)
  • May provide mild relief in constipation (Hoffmann, 2003, p. 549)


Preparation & Dosage

Tincture: (1:5 in 45%) 2-4mL/tds

Infusion: 1-2tsp/1cup water drunk hot as possible/tds

(Hoffmann, 2003, p. 549)


  • According to secondary sources, boneset should not be taken for over 2 weeks at a time
  • Individuals with liver damage
  • Individuals with electrolyte abnormalities
  • Individuals with cardiac conditions
  • Safety not yet determined in pregnancy and lactation

(Giese et al., 2013)



Known allergy to members of Asteracea family (Hoffmann, 2003, p. 549)



For influenza, combines well with Yarrow, Elder flower, Cayenne or Ginger (Hoffmann, 1990, p. 184)



Giese, N., Brigham, A., Costa, D., Le, T., Ulbricht, C., & Weissner, W. (2013). Boneset (Eupatorium perfoliatum). Natural Standard Professional Monograph. Retrieved from:

Hoffmann, D. (2003). Medical Herbalism: The Science and Practice of Herbal Medicine. Rochester Vermont: Healing Arts Press.

Hoffmann, D. (1990). Holistic Herbal. London: Thorsons

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